M4678-01

Moxidectin

Size

£327.00

SKU:: M4678-01
Molecular Weight:: 639.8
Purity:: ~95% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 113507-06-5
Format:: Supplied as a white solid.
Extra Details:: Moxidectin is a semi-synthetic milbemycin derived from nemadectin by selective oxidation followed by methyloximation. Moxidectin was patented in 1991 as an anthelmintic for internal parasite control. The presence of the methyloxime affords moxidectin a greater hydrophobicity and longer biological half-life compared to nemadectin. It binds selectively to parasite glutamate-gated chloride neurotransmission leading to ion channels and disrupts paralysis and death of the parasite. Source: Semi-synthetic Moxidectin Molecular Weight: ~639.8 Solubility: Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.