M3887-49Q
MHC Class I (H-2 class I histocompatibility antigen, K-B alpha chain precursor, H-2 Class I histocompatibility antigen, K-D alpha chain precursor, H-2 class I histocompatibility antigen, K-K alpha chain precursor, H-2 class I histocompatibility antigen, K-Q alpha chain, H-2 class I histocompatibility antigen, K-W28 alpha chain precursor, H2-K, H-2K, H-2K(B), H-2K(d), H-2K(D), H-2K(K), H-2K(Q), MGC7052, MHC I)
Size
£745.00
- SKU:
- M3887-49Q
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Clone:
- 9G232 (ER-HR52)
- Format:
- Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
- Extra Details:
- The primary immunological function of MHC molecules is to bind and present antigenic peptides on the surfaces of cells for recognition by the antigen-specific T cell receptors (TCRs) of lymphocytes. MHC class I molecules are expressed on the surfaces of most cells and are recognized by CD8-positive cytotoxic T-cells, an essential step for initiating the elimination of virally infected cells by T-cell-mediated lysis. MHC class I molecules are heterodimers composed of an alpha (44kD) and a beta (beta microglobulin, 11kD) subunit. The first two structural domains of the alpha subunit associate to form the peptide-binding pocket. Applications: Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 1:50 Immunohistochemistry (frozen): 1:50 The antigen is glutaraldehyde (0.05%) and paraformaldehyde (1%) resistant. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice