mGluR6 (Metabotropic Glutamate Receptor)

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£626.00

SKU:: M3884-80A
Purity:: Purified by immunoaffinity chromatography
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: C-terminus of rat mGluR6 (AAPPQNENAEDAK). Cellular Localization: Integral memrane protein.
Format:: Supplied as a liquid in Tris glycine, 0.02% sodium azide.
Extra Details:: Metabotropic Glutamate Receptor 6 (mGluR6) is a member of the G protein-coupled receptor III family, linked to the inhibition of the cyclic AMP cascade. mGluR6 displays the highest sequence similarity to mGluR4 among the metabotropic receptor subtypes and inhibits the forskolin-stimulated cyclic AMP accumulation in CHO cells transfected with the cloned cDNA. mGluR6 antibodies are most useful for G protein-coupled receptor research and metabolism studies. Applications: Suitable for use in Immunofluorescence/Immunocytochemistry and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000; Recognizes a band at ~96kD. Immunofluorescence (IC): 1:100-1:500 Neurons of expected mouse brain regions stain well. Staining is not recommended for human or rat tissues. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.