mGluR2,3 (Metabotropic Glutamate Receptor 2/3, Metabotropic Gutamate Receptor 2, mGluR2, Metabotropic Glutamate Receptor 3, mGluR3, Gprc1b, Gprc1c, Grm2, Grm3)

Size

£492.00

SKU:: M3884-76G
Purity:: Purified by affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to aa860-872, NGREVVDSTTSSL, of the rat mGlurR2/3 protein. Species Sequence Homology: human and mouse; 100%; conserved between mGluR2 and mGluR3.
Format:: Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Extra Details:: Metabotropic glutamate receptors are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain. Applications: Suitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:500 Immunohistochemistry: 1:250 Immunocytochemistry: 1:250 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice