M3007-14-APC
c-Met, CT (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR) (APC)
Size
£615.00
- SKU:
- M3007-14-APC
- Purity:
- Purified
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide derived from the human c-Met C-terminus sequence, conjugated to a carrier protein. Expected Staining Pattern: Cytoplasmic
- Format:
- Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
- Extra Details:
- c-MET (HGFr) is a proto-oncogene (locus 7q21-q31) protein and a cell-surface receptor of hepatocyte growth factor. It has tyrosine kinase activity. It consists of alpha (50kD) and beta (145kD) subunits linked by a disulfide bond. c-Met is overexpressed in many cancers. The MET gene is often amplified between tumorgenesis and metastasis. It has been suggested that c-Met is useful as a prognostic marker in numerous cancers including: breast cancer, gastric carcinoma, endometrial carcinoma and others. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: Frozen and formalin-fixed paraffin-embedded sections. Epitope retrieval required using citrate buffer, pH 6.0 is required. Enzyme digestion is not required. Optimal dilutions to be determined by the researcher. Positive Control: Breast carcinoma Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice