M3007-13L

MET, phosphorylated (Tyr1356) (HGF receptor, HGFR, Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, SF Receptor, HGF/SF Receptor, Tyrosine-Protein Kinase Met, Proto-Oncogene c-Met)

Size

£696.00

SKU:: M3007-13L
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: KLH-conjugated synthetic phosphopeptide mapping to a fragment of amino acids surrounding Y1356 of human MET, UniProt Accession #NP_000236; P08581 (4=4 branches MAPS).
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Applications: Suitable for use in ELISA and Dot Blot. Other applications not tested. Recommended Dilutions: ELISA: 1:1000 Dot Blot: 1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.