M2867-76F

Melanin Concentrating Hormone (MCH) (salmon)

Size

£599.00

SKU:: M2867-76F
Molecular Weight:: 2099.48
Purity:: ≥99% (HPLC.)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: White to off-white powder
Extra Details:: Cyclic neuropeptide originally discovered in the pituitary gland of the chum salmon, famous for causing skin lightening by concentrating melanin. Consists of a specific amino-acid ring structure and acts as a vital neuro-hormone and neurotransmitter across vertebrates. Aggregates melanosomes inside fish dermal melanophores to turn skin pale on bright or light backgrounds. Acts as a powerful appetite stimulator (orexigenic peptide) in mammals and other vertebrates. Participates in regulating energy homeostasis, stress axes, and the sleep-wake cycle. Synonyms: Asp-Thr-Met-Arg-Cys-Met-Val-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Glu-Val; (6S,9S,12S,15S)-1,15-diamino-6-(((3R,8R,11S,14S,20S,23S,26S,29S,34aS)-3-(((S)-1-(((S)-4-carboxy-1-(((S)-1-carboxy-2-methylpropyl)amino)-1-oxobutan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamoyl)-20,29-bis(3-guanidinopropyl)-26-(4-hydroxybenzyl)- Sequence: Asp-Thr-Met-Arg-Cys-Met-Val-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Glu-Val Disulfide bridge(s): Cys5-Cys14 CAS No: 87218-84-6 Molecular Formula: C₈₉H₁₃₉N₂₇O₂₄S₄ Molecular Weight: ~2099.48 Appearance: White to off-white powder Purity: ≥99% (HPLC.) Solubility: Water Storage and Stability: Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.

Shipping Conditions:: Ambient