MEIS1 (Homeobox Protein Meis1)

Size

£537.00

SKU:: M2862-08A
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to aa170-220 of MEIS1.
Format:: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Extra Details:: MEIS1, also known as Homeobox protein Meis1, is a nuclear protein belonging to the TALE/MEIS homeobox family with a homeobox DNA-binding domain. It acts as a transcriptional regulator of PAX6 (Paired box protein Pax-6). It is a protein required for hematopoiesis, megakaryocyte lineage development and vascular patterning. Expression is seen at low levels in normal immunohepatopoietic tissues, and in a subset of myeloid leukemia cell lines, with the highest expression seen in those with a megakaryocytic-erythroid phenotype. It is also expressed at high levels in the cerebellum. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 2-4ug/ml Immunohistochemistry (formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Brain Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.