M2800-03A-ML650
MDM2 (Murine Double Minute-2) (MaxLight 650)
Size
£843.00
- SKU:
- M2800-03A-ML650
- Purity:
- Purified by Protein G affinity chromatography from tissue culture supernatant.
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to aa154-167, CSRPSTSSRRRAISE, of human MDM2.
- Clone:
- 3H2649 (SMP14)
- Format:
- Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650.
- Extra Details:
- MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. MDM2 forms a complex with p53 leading to p53 inhibition. MDM2 also acts to stimulate cell proliferation via its induction of transcription factors such as E2F1 and DPI. MDM2 is overexpressed in a range of human malignancies, including soft tissue sarcomas, breast cancer and bladder cancer. Applications: Suitable for use in Immunohistochemistry and Immunoprecipitation. Other applications have not been tested. Recommended Dilutions: Optimal working dilutions to be determined by researcher. Hybridoma: X63-Ag8.653 myeloma cells with spleen cells from Balb/c mice. Recommended Positive Control: Human Breast Carcinoma Recommended Negative Control: I1904-78R: IgG1 Murine Negative Control Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice