M2425-10G

Matrix Metalloproteinase 9 (MMP-9, Collagenase 4, Gelatinase B)

Size

£422.00

SKU:: M2425-10G
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Full-length recombinant protein corresponding to MMP-9
Clone:: 5K164
Format:: Supplied as a liquid in Borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
Extra Details:: Matrix metalloproteinases (MMPs) are a family of at least 20 structurally related, zinc-containing enzymes that have the ability to breakdown connective tissue. MMP-9 is also known as gelatinase B and 92kD gelatinase. MMP-9, along with MMP-2, belongs to the gelatinase group of MMP’s which have three repeats of a type II fibronectin domain inserted in the catalytic domain. MMP-9 has shown direct and indirect substrate specificity to collagens IV, V, X and XIV, gelatin, elastin, proteoglycans, plasminogen, aggrecan, galectin-3, entactin, fibrillin, fibrin, IL-1beta, amyloid beta peptide and myelin basic protein. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: ELISA: ≤1ug/ml Immunohistochemistry (FFPE): ≤5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.