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M2420-50G

Matrix Metalloproteinase 2 (MMP-2, Collagenase IV, Gelatinase A)

Size

£422.00

SKU:
M2420-50G
Application:
IHC-Fr
Purity:
Purified
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Mouse
Immunogen:
Recombinant MMP-2
Clone:
SB13a
Format:
Supplied as a liquid in 100mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
Extra Details:
Matrix metalloproteinases (MMPs) are a family of at least 20 structurally related, zinc-containing enzymes that have the ability to breakdown connective tissue. MMP-2 is also known as gelatinase A, 72kD gelatinase, type IV collagenase and TBE-1. MMP-2, along with MMP-9, belongs to the gelatinase group of MMP’s which have three repeats of a type II fibronectin domain inserted in the catalytic domain. MMP-2 has shown direct and indirect substrate specificity to collagens I, IV, V, VII, X and XIV, gelatin, elastin, laminin-1, laminin-5, myelin basic protein, MMP-1, MMP-9, and MMP-13. 1-15 Applications: • Immunohistochemistry (frozen and paraffin embedded sections) Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice