M2412-27

Masitinib, Free Base (AB-1010)

Size

£262.00

SKU:: M2412-27
Molecular Weight:: 498.64
Purity:: ≥99% (HPLC); ≥99% (TLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 790299-79-5
Format:: Off-white to pale, yellow powder.
Extra Details:: Masitinib mesylate (AB1010) is a protein tyrosine kinase inhibitor. In vitro it has greater activity and selectivity than imatinib mesylate against the wild-type c-Kit receptor and the mutated form in the juxtamembrane region. It also inhibits the PDGF and FGFR3 receptors. Synonyms: 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide; AB-1010; Kinavet; Masivet CAS No: 790299-79-5 Molecular Formula: C28H30N6OS Molecular Weight: 498.64 Appearance: Off-white to pale, yellow powder. Purity: ≥99% (HPLC); ≥99% (TLC) Melting Point: 98-122°C Solubility: Soluble in DMSO at 200mg/ml; very poorly soluble in ethanol or water; maximum solubility in plain water is estimated to be about 10-20uM; buffers, serum, or other additives may increase or decrease the aqueous solubility. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.