M2378-02E

MARCO (Macrophage Receptor MARCO, Macrophage Receptor with Collagenous Structure, AI323439, Ly112, Scara2)

Size

£812.00

SKU:: M2378-02E
Purity:: Purified by Protein G affinity chromatography from tissue culture supernatant.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rat
Immunogen:: CHO cells expressing mouse MARCO.
Clone:: 6A441 (ED31)
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: MARCO is expressed by distinct populations of macrophages in the spleen and lymph nodes, but is rapidly induced on macrophages in other tissues (e.g. Liver Kupffer cells) during infection or LPS treatment. Clone ED31 binds to the C-terminal cysteine rich domain of MARCO, and has been shown to block ligand binding. Applications: Suitable for use in Immunohistochemistry, Immunofluorescence and Western Blot. Not suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Frozen): 1:200-1:400 Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from immunized rats. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.