M2353-70E

MAP Kinase Interacting Serine/threonine Kinase 1, Recombinant, Human, GST-Tag (MAP Kinase Signal-integrating Kinase 1, MAPK Signal-integrating Kinase 1, MKNK1, MNK1)

Size

£912.00

SKU:: M2353-70E
Molecular Weight:: 74
Purity:: ≥70%
Storage Conditions:: -70°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 25mM Tris-HCl, pH 8.0, 100mM sodium chloride, 0.05% Tween 20, 3mM DTT, 30% glycerol.
Extra Details:: MNK1 may play a role in the response to environmental stress and cytokines. It appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. Source: Recombinant human MNK (T385D), aa2-end (deletion 165-205aa), with N-terminal GST tag, expressed in a Baculovirus infected Sf9 cell expression system. Molecular Weight: 74kD Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months.