M2256-01L
MRC1 (Macrophage Mannose Receptor 1, MMR, C-type Lectin Domain Family 13 Member D, C-type Lectin Domain Family 13 Member D-like, Macrophage Mannose Receptor 1-like Protein 1, CD206, CLEC13D, CLEC13DL, MRC1L1) (APC)
Size
£767.00
- SKU:
- M2256-01L
- Application:
- Flow Cytometry
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant corresponding to aa19-1383 from human MRC1 extracellular domain expressed in NSO cell line.
- Clone:
- 12K134
- Format:
- Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with Allophycocyanin (APC).
- Extra Details:
- MMR, also known as CD206 and MRC1, is a 17kD scavenger receptor that belongs to the C-type lectin protein family. MMR is expressed on tissue macrophages, myeloid dendritic cells, and liver and lymphatic endothelial cells. The extracellular region of MMR is composed of an N-terminal cysteine-rich domain, one fibronectin type II repeat, and eight C-type lectin carbohydrate recognition domains. MMR mediates the phagocytosis of sulfated N-acetylgalactosamine-containing molecules including those found on a variety of microorganisms. Within the extracellular region, mouse MMR shares 83% and 92% aa sequence identity with human and rat MMR. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Excitation: 620-650nm Emission: 660-670nm Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. APC is light sensitive.
- Shipping Conditions:
- Blue Ice