L8015-01-HRP

Lymphotoxin beta Receptor (Lymphotoxin B Receptor, LTbetaR, LT-beta-R, LTBR, AI256028, CD18, Ltar, TNF-R-III, Tnfbr, TNFRrp, TNFR-RP, TNFR2-RP, Tumor Necrosis Factor C Receptor, TNFCR, Tumor Necrosis Factor Receptor Superfamily Member 3, Tnfrsf3) (HRP)

Size

£882.00

SKU:: L8015-01-HRP
Purity:: Purified by Protein G affinity chromatography from tissue culture supernatant.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rat
Immunogen:: Recombinant protein corresponding to the extracellular domain of mouse LT beta R
Clone:: 5G11b
Format:: Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).
Extra Details:: Lymphotoxin beta receptor is 385 amino acid (415 aa including 30 aa signal peptide) ~50kD type 1, single pass transmembrane glycoprotein and member of the tumor necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. L8015-01 is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release (Hehlgans et al. 2003). L8015-01 is routinely tested on WEH164S cells. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.

Shipping Conditions:: Blue Ice