L8015-01-BIOTIN
Lymphotoxin beta Receptor (Lymphotoxin B Receptor, LTbetaR, LT-beta-R, LTBR, AI256028, CD18, Ltar, TNF-R-III, Tnfbr, TNFRrp, TNFR-RP, TNFR2-RP, Tumor Necrosis Factor C Receptor, TNFCR, Tumor Necrosis Factor Receptor Superfamily Member 3, Tnfrsf3) (Biotin)
Size
£882.00
- SKU:
- L8015-01-BIOTIN
- Application:
- Flow Cytometry
- Purity:
- Purified by Protein G affinity chromatography from tissue culture supernatant.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Recombinant protein corresponding to the extracellular domain of mouse LT beta R
- Clone:
- 5G11b
- Format:
- Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.
- Extra Details:
- Lymphotoxin beta receptor is 385 amino acid (415 aa including 30 aa signal peptide) ~50kD type 1, single pass transmembrane glycoprotein and member of the tumor necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. L8015-01 is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release (Hehlgans et al. 2003). L8015-01 is routinely tested on WEH164S cells. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice