L4502-21K

LRRK2 (Leucine-rich Repeat Kinase 2, RIP7, PARK8, Dardarin) (Not for Export EU)

Size

£735.00

SKU:: L4502-21K
Application:: IHC-Fr
Purity:: Serum
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Sheep
Immunogen:: Synthetic peptide corresponding to human LRRK2 (LKRKRKILSSDDSLRSS; aa946-962) conjugated to the Blue Carrier Protein.
Format:: Supplied as a lyophilized powder. No preservative added. Reconstitute with 100ul sterile ddH2O.
Extra Details:: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. Applicatons: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (frozen): 1:500-1:10,000 Optimal dilution determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.