L3505-50

Low Density Lipoprotein Receptor Adapter Protein 1 (LDLRAP1, Autosomal Recessive Hypercholesterolemia Protein, ARH, ARH1, ARH2, DKFZp586D0624, FHCB1, FHCB2, MGC34705, OTTHUMP00000008526) (Azide Free)

Size

£685.00

SKU:: L3505-50
Purity:: Purified by ammonium sulfate precipitation.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Full length recombinant protein corresponding to a region near aa1-264 of human LDLRAP1 (AAH29770) with GST tag.
Clone:: 11C381
Format:: Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
Extra Details:: The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia. Applications: Suitable for use in ELISA, Immunofluorescence, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilutions: Immunohistochemistry: 1.5ug/ml ELISA: 3ng/ml-1ug/ml Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.