L2028-55
Leukocyte Immunoglobulin-like Receptor 6 (LIR6, LILRA1, CD85i)
Size
£856.00
- SKU:
- L2028-55
- Purity:
- Purified by Protein G affinity chromatography from culture supernatant.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to Pro17-Asn461 from human Leukocyte Immunoglobulin-like Receptor 6, expressed in NS0 cells.
- Clone:
- 7H127
- Format:
- Supplied as a lyophilized powder from PBS pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
- Extra Details:
- Leukocyte Immunoglobulin-like Receptor 6 (LIR6), also called LILRA1 or CD85i, is a glycoprotein member of the LIR family of leukocyte Ig-like receptors. As an activating LIR, LIR-6 has a short cytoplasmic tail and a charged aa within the TM domain which interacts with FcRγ. Both four (LIR-6a) and two (LIR-6b) Ig-like domain forms are expressed by monocytes and B cells. Human LIR6 has no non-primate ortholog, but shows up to 80% aa identity with human ILT-1c and KIR-p91/PIR-B. A mouse homolog, gp49B2, has structural similarity but limited sequence identity. Applications: Suitable for use in Western Blot and Direct ELISA. Other applications not tested. Recommended Dilutions: Western Blot: 1ug/ml. Using recombinant human LIR6. Optimal dilutions should be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice