Leucine Rich Repeat and Ig Domain Containing 1, NT (Leucine-rich Repeat and Immunoglobulin-like Domain-containing Nogo Receptor-interacting Protein 1, Lingo 1, LINGO1, Lingo-1, FLJ14594, Leucine-rich Repeat and Immunoglobilin Domain-containing Protein 1, Leucine-rich Repeat Neuronal Protein 1, LERN1, Leucine-rich Repeat Neuronal Protein 6A, LRRN6A, MGC17422, UNQ201/PRO227)

Size

£696.00

SKU:: L2020-73N
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 62-92 in the N-terminal region of human LRRN6A, UniProt Accession #Q96FE5. Species Sequence Homology: chicken, monkey and mouse
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: LINGO1 is a functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. It is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.