Leucine Rich Repeat and Ig Domain Containing 1, NT (Leucine-rich Repeat and Immunoglobulin-like Domain-containing Nogo Receptor-interacting Protein 1, Lingo 1, LINGO1, Lingo-1, FLJ14594, Leucine-rich Repeat and Immunoglobilin Domain-containing Protein 1, Leucine-rich Repeat Neuronal Protein 1, LERN1, Leucine-rich Repeat Neuronal Protein 6A, LRRN6A, MGC17422, UNQ201/PRO227) (Azide free) (HRP)

Size

£889.00

SKU:: L2020-73N-HRP
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 62-92 in the N-terminal region of human LRRN6A, UniProt Accession #Q96FE5. Species Sequence Homology: chicken, monkey and mouse
Format:: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Extra Details:: LINGO1 is a functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. It is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.

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