Leflunomide-d4 (5-Methylisoxazole-4-[4-trifluoromethylcarboxanilide]-d4)

Size

£422.00

SKU:: L1662-92D
Molecular Weight:: 274.23
Purity:: ~90%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 1189987-23-2
Format:: Supplied as an off-white crystalline solid
Extra Details:: An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Source: Synthetic Purity: ~90% Form: Supplied as an off-white crystalline solid Melting Point: 159-161°C Solubility: Chloroform, Methanol Method for Determining Identity: Proton NMR and Mass Spectroscopic Analysis. TLC Conditions: SiO2: Hexane: Ethyl Acetate; 3:2; Visualized with UV and KMnO4; Single spot; Rf=0.6. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.