L1237-20
LANA 2 (Latency-Associated Nuclear Antigen 2, LANA-2)
Size
£594.00
- SKU:
- L1237-20
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant LANA2 fusion protein. Cellular Localization: Nuclear.
- Clone:
- 8L564
- Format:
- Supplied as a liquid in PBS, 0.09% sodium azide.
- Extra Details:
- LANA2 (latency-associated nuclear antigen) is an inhibitor of p53-induced transcription in reporter assays and may be an apoptosis antagonist. It is a nuclear protein associated with Kaposi's sarcoma-associated herpes virus (KSHV), or human herpes virus 8. It is found in abundance in the nuclei of cultured cells from KSHV-infected hematopoietic tissues, such as PEL (primary effusion lymphoma) and CD (multicentric Castleman's disease). It does not appear to be expressed in KS (Kaposi's sarcoma) lesions. Applications: Suitable for use in ELISA, Immunohistochemistry, Immunofluorescence, Western Blot and Immunoprecipitation. Knockout validated reported in scientific literature. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Frozen and paraffin): 1:10-1:2000 ELISA: 1:100-1:2000 Immunofluorescence (IC): 1:10-1:2000 Western Blot: 2-4ug/ml detects a band at ~66-70kD. Immunoprecipitation: 1:10-1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice