L1233
Laminin Receptor (RPSA, 37LRP, 67LR, LAMBR, LAMR1, LBP, LRP, SA, p40, 40S ribosomal protein SA, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4)
Size
£978.00
- SKU:
- L1233
- Purity:
- Purified by ammonium sulfate precipitation from ascites.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Small cell lung carcinoma N592 live cells. MW of Antigen: 67kD. Cellular Localization: Cell membrane with some cytoplasmic
- Clone:
- 3F252 (MLuC5)
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
- Extra Details:
- Laminin, one of the major glycoproteins of basement membrane, displays multiple biological activities which are mediated through its interaction with specific cell membrane receptors. Overexpression of laminin receptor is reportedly an independent prognostic factor in breast cancer and correlates with the dissemination of the tumor cells in bone marrow. Laminin receptor appears to play an important role in tumor invasion and metastasis. Applications: Suitable for use in Flow Cytometry, Immunofluorescence, Immunohistochemistry and Inhibition. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry (Formalin/paraffin): 4-8ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues is improved by boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Inhibition: Partially inhibits the binding of soluble human laminin. Optimal dilutions to be determined by the researcher Positive Control: Breast carcinoma, Placenta Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice