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L1226-12

Laminin, beta 1 (LAMB1, CLM, Laminin Subunit beta-1, Laminin B1 Chain, Laminin-1 Subunit beta, Laminin-2 Subunit beta, Laminin-6 Subunit beta, Laminin-8 Subunit beta, Laminin-10 Subunit beta, Laminin-12 Subunit beta, MGC142015)

Size

£934.00

SKU:
L1226-12
Purity:
Ascites
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Mouse
Immunogen:
Partially pepsin-digested laminins from human placenta
Clone:
DG10
Format:
Supplied as a liquid in PBS, 1% BSA, 0.09% sodium azide.
Extra Details:
Laminin, a major structural glycoprotein of the basement membranes, is an attachment and survival factor for epithelial cells and can also promote the growth of epithelial cells. Laminin plays an important role in both the structural organization of basement membranes and in the anchorage of cells. The monoclonal antibody, DG10 and BC17 against laminin chain beta1 and gamma1, respectively can be widely applied in immunohistochemical studies as all basement membranes contain laminin trimers containing these chains. Antibodies to laminin chains are useful in basic biology studies as well as in pathological studies concerning, for instance, the integrity of the basement membranes in carcinomas. Clone DG10 against laminin beta1-chain is apparently one of the few laminin antibodies working perfectly in immunoblotting, thus making it especially valuable for biochemical studies. Applications: Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications tested. Recommended Dilution: Western Blot: Reacts under reducing and nonreducing conditions Immunohistochemistry: Frozen Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice