L0010-01
L1 Cell Adhesion Molecule (L1CAM)
Size
£704.00
- SKU:
- L0010-01
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- 3T3 fibroblasts transfected with the human L1 protein
- Clone:
- 6A103
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide
- Extra Details:
- The L1 adhesion molecule is a 200-220kD membrane glycoprotein of the immunoglobulin superfamily. Initially studied in the nervous system, L1 is involved in important processes such as neuron-neuron adhesion and migration, axonal outgrowth and fasciculation, myelination, and synaptic plasticity. Mutations in the L1 gene product have been shown to cause abnormal brain development. Outside the nervous system, L1 is expressed in hematopoietic and certain epithelial cells in humans. L1 is also active in the mitogen-activated protein kinase (MAPK) signaling cascade. Applications: Suitable for use in ELISA, Immunopreciptitation, Immunofluorescence and Immunocytochemistry. Other applications have not been tested. Recommended Dilution: ELISA: 0.1-1ug/ml Immunoprecipitation: 5-10ug/test Immunofluorescence: 5-10ug/test Immunocytochemistry: 0.5-5ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human L1-transfected rat B28 cells Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice