K9001-07D

Kv1.2 (Kcna2, Voltage-gated Potassium Channel)

Size

£837.00

SKU:: K9001-07D
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to rat Kv1.2. Cellular Localization: Membrane; Multi-pass membrane protein
Clone:: 11C244 (K14/16)
Format:: Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
Extra Details:: Potassium channel Kv1.2 is one of many different types of potassium channels in the cell. The Kv family of potassium channels seem to have a conserved homotetramer formation consisting of four voltage sensors and one pore domain. Kv1.2 cooperates with cortactin (an actin cytoskeleton-binding protein) and together they may have a part in the regulation of the ionic current. Applications: Suitable for use in Western Blot, Immunofluorescence and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Western Blot: 0.5ug/ml detects Kv1.2 on 10ug of rat brain membrane tissue lysate. Immunohistochemistry (Paraffin): 1:500. Heat-induced epitope retrieval in citrate buffer, pH 6.0 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.