K6751

KSHV ORF73 (Kaposi's Carcinoma-associated Herpes Virus, Glycoprotein B-like, Human Herpes Virus 8, HHV8)

Size

£484.00

SKU:: K6751
Purity:: Purified by Protein G affinity chromatography
Storage Conditions:: 20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to aa122-329 from human ORF73/HHV8, expressed in E. coli.
Clone:: 10C301
Format:: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide
Extra Details:: ORF73 protein of human Herpes virus 8(HHV-8) is a Kaposi's sarcoma-associated Herpes virus (KSHV) latent protein which has been suspected of playing a crucial role in modulating viral and cellular gene expression. ORF73 is associated with cellular chromatin and stays on the chromosomes during cell division. It maintains the viral genomes during cell division by tethering the viral episomes to the chromosomes. It binds directly to replication origin recognition complexes (ORCs) that are primarily associated with the terminal repeat (TR) region of the HHV-8 genome. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Immunohistochemistry: 1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.