Kazusamycin A (Kazusamycin, Hydroxyleptomycin B, Hydroxyelactocin, Antibiotic CL 1957B, Antibiotic PD 114721)

Size

£559.00

SKU:: K0108-85
Molecular Weight:: 556.7
Purity:: >95% by HPLC
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 92090-94-3
Extra Details:: Kazusamycin A is a minor member of the leptomycin complex isolated from some Streptomyces species. It is an hydroxylated analogue of Leptomycin B, a nuclear export inhibitor. Kazusamycin A exhibits potent antitumour activity both in vitro and in vivo against P388 and L1210 cell lines and also shows strong antibacterial and antifungal activity. Purity: >95% by HPLC Solubility: Soluble in ethanol or methanol. Ethanol recommended. Unstable in DMSO. Related to: Anguinomycin A, Leptomycin A, Leptomycin B, Kazusamycin B,