K0102-09J
KPNA4 (Importin alpha-4 Subunit, Karyopherin alpha-4 Subunit, Importin alpha Q1, Importin alpha-4, QIP1)
Size
£642.00
- SKU:
- K0102-09J
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Goat
- Immunogen:
- Synthetic peptide corresponding to C-NSSANVPTEGFQF, from KPNA4, at C-terminal (NP_002259.1).
- Format:
- Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
- Extra Details:
- The nuclear import of karyophilic proteins is directed by short aa sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 0.2-1ug/ml Immunohistochemistry (Paraffin embedded): Human Testis - shows strong nuclear staining of some cells in the seminiferous tubules. Recommended concentration, 3ug/ml. Human Small Intestine - shows pixulate staining in nuclei of enterocytes, 1-2ug/ml. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice