J2499-95G

JNK1 (Jun Kinase 1, c-Jun N-terminal Kinase, Stress Activated Protein Kinase alpha, SAPKa, JAK1A, JNK46, JNK1 alpha 2, JNK21B1/2, Mitogen Activated Protein Kinase 8, MAPK8, MK08, p54 gamma, PRKM8) (Not for Export EU)

Size

£594.00

SKU:: J2499-95G
Purity:: Serum
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant corresponding to aa228-451 from the C-terminus of C. elegans JNK1 alpha protein. Cellular Localization: Neuronal
Format:: Supplied as a liquid, 0.05% sodium azide.
Extra Details:: The insulin signaling pathway plays a pivotal role in lifespan regulation and stress resistance in many diverse organisms. Components of the JNK (c-Jun N-terminal kinase) signaling pathway have been shown to interact with the insulin signaling pathway. The JNK family is a subgroup of the mitogen-activated protein kinase superfamily and is part of a signal transduction cascade that is activated by cytokines and by exposure to environmental stresses. Thus, JNK1 plays a role in regulating both life span and stress resistance. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:2000. A band was identified at ~53kD for JNK1 alpha and ~42kD for JNK1 beta. Immunohistochemistry: Paraffin sections Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.