J1260-03A

JIK (JNK/SAPK-inhibitory Kinase, Jun Kinase Inhibitory Kinase, Cutaneous T-cell Lymphoma-associated Antigen HD-CL-09, CTCL-associated Antigen HD-CL-09, Dendritic Cell-derived Protein Kinase, DPK, KDS, Kinase from Chicken Homolog A, hKFC-A, MAP3K18, Serine/threonine-protein Kinase TAO3, TAO Kinase 3, TAOK3, Thousand and One Amino Acid Protein 3)

Size

£642.00

SKU:: J1260-03A
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to CHKKDHVFIRDEAGHGD, from human TAOK3, at the internal region of the protein (NP_057365.3).
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: TAOK3, also known as DPK or JIK, is a member of the TAO subfamily of serine/threonine kinases. The activity of TAOK3 can be negatively regulated by tyrosine kinase receptors, such as EGF receptor activation. In addition, the downstream targets of TAOK3 inhibit, rather than enhance, JNK/SAPK activation. Therefore, TAOK3 has been named as a JNK/SAPK-inhibitory kinase. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 0.3-1ug/ml, observed in human liver lysate on ~100kD bands Immunohistochemistry (Paraffin): 2-3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.