I8782-60
ISLR2 (Immunoglobulin Superfamily Containing Leucine-Rich Repeat 2, SST273)
Size
£825.00
- SKU:
- I8782-60
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Sheep
- Immunogen:
- Recombinant protein corresponding to Cys20-Leu590 at the extracellular domain of human ISLR-2, expressed in NS0 cells.
- Format:
- Supplied as a lyophilized powder from PBS, pH 7.4. Reconstitute with 500ul sterile PBS.
- Extra Details:
- ISLR-2 (Ig-superfamily containing LRR protein 2; also KIAA1465) is a 100-110kD member of the LRR family of proteins. It is expressed on developing motor, sensory and interneurons. Mature human ISLR-2 is 727aa in length. It is a type I transmembrane glycoprotein that contains a 571 aa extracellular domain (ECD) and a 135 aa cytoplasmic region. The ECD shows multiple LRRs (aa50-227) and one Ig-like domain (aa233-371). One alternate splice form may exist that shows a deletion of aa160-570. Over aa20-590, human ISLR-2 is 89% aa identical to both canine and mouse ISLR-2. Applications: Suitable for use in Direct ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 0.1ug/ml using Recombinant Human ISLR‑2 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice