I8700-18P

IRS-2, phosphorylated (Tyr978) (Insulin Receptor Substrate 2, IRS2)

Size

£696.00

SKU:: I8700-18P
Purity:: Purified by Protein A and peptide affinity chromatography
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: KLH-conjugated synthetic phosphopeptide corresponding to amino acids residues surrounding Y978 of human IRS2. Species Sequence Homology: mouse
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. Applications: Suitable for use in ELISA and Dot Blot. Other applications not tested. Recommended Dilutions: Dot Blot: 1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.