I8449-05A-ML650

IP-10 (Interferon gamma Inducible 10kD Protein, 10kD Interferon gamma Induced Protein, Chemokine (C-X-C Motif) Ligand 10, C-X-C Motif Chemokine 10, CXCL10, CRG-2, C7, Gamma IP-10, gIP-10, Interferon Inducible Cytokine IP-10, IFI10, INP10, MOB-1, Small Inducible Cytokine B10, SCYB10) (MaxLight 650)

Size

£789.00

SKU:: I8449-05A-ML650
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to mouse IP-10, expressed in E. coli.
Format:: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Extra Details:: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. Interferon-gamma-inducible 10kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis. Applications: Suitable for use in FLISA, Western Blot and Neutralization. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Country of Origin: USA Note: Applications are based on unconjugated antibody.

Shipping Conditions:: Blue Ice