I8443-93G

Interleukin 34 (IL-34, C16orf77, chromosome 16 open reading frame 77, hypothetical protein MGC34647)

Size

£1,068.00

SKU:: I8443-93G
Purity:: Purified by Protein G affinity chromatography from hybridoma culture supernatant.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to Asn21-Pro242 from human IL-34, expressed in NS0 cells.
Clone:: 11D10
Format:: Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.
Extra Details:: Interleukin 34 (IL-34) is secreted as a homodimer consisting of 39kD monomers. It belongs to no known cytokine family. The mature chain contains one potential site for N-linked glycosylation. IL-34 is widely expressed, but it is most abundant in the spleen. The receptor for IL-34 is colony-stimulating factor 1 receptor (CSF-1R). Functionally, IL-34 stimulates monocyte viability. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA (Capture): 2-8ug/ml using I8443-93E as detection antibody Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.