I8442-26
Interleukin 21R, NT (IL-21R NT)
Size
£655.00
- SKU:
- I8442-26
- Application:
- WB
- Purity:
- Immunoaffinity purified IgG
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide (CPDLVCYTDYLQT) corresponding to amino acids 20 to 32 of human IL-21R precursor (1).
- Format:
- 100ug in 200ul of PBS, 0.02% sodium azide.
- Extra Details:
- A novel cytokine related to IL2 and IL15 was recently identified and designated IL-21 (1). The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family (1,2). IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling (3,4). Both IL-21R and the gc are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations. Applications: Suitable for use in Western Blotting. Other applications not tested. Recommended Dilution: 0.5-1ug/ml Optimal dilutions to be determined by the researcher. Human Raji and A431 cell lysates can be used as positive control. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice