I8439-35H
Interleukin-17 Receptor A (IL17RA, IL-17RA, CDw217, CD217) (APC)
Size
£793.00
- SKU:
- I8439-35H
- Application:
- Flow Cytometry
- Purity:
- Purified by Protein G affinity chromatography from cell culture supernatant.
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Recombinant protein corresponding to Ser32-Trp322 from the extracellular domain of mouse IL-17 R, expressed in NSO cell line.
- Clone:
- 12K116
- Format:
- Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with Allophycocyanin (APC).
- Extra Details:
- Interleukin-17 is a pleotropic cytokine expressed by T cells. IL-17 binds to the IL-17 receptor (IL-17 R), which shares no homology with any other known family of receptors. While the expression of IL-17 is restricted to activated T cells, the IL-17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The aa sequence of mouse IL-17 R is 69% identical to human IL-17 R. The signaling events mediated by IL-17 include activation of NF-KB and JNK, and require TNF receptor-associated factor 6 (TRAF6) in the signaling pathway. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 10ul labels 10e6 cells in EL‑4 mouse cell line Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Blue Ice