I8439-04GX

Interleukin 17 (IL-17, CTLA8, IL-17A, Interleukin-17A precursor, Cytotoxic T-lymphocyte-associated antigen 8) (Azide Free)

Size

£487.00

SKU:: I8439-04GX
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rat
Immunogen:: Recombinant protein corresponding to mouse IL-17 expressed in E. coli.
Clone:: 5K131
Format:: Supplied as a liquid in PBS. No preservative added.
Extra Details:: Interleukin 17 is a proinflammatory cytokine produced by activated T cells. It regulates the activities of NF-kappaB and mitogen-activated protein kinases and can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). Interleukin-17 (IL-17) and its cognate receptor, IL- 17R, are examples of cytokine receptor pairs. IL-17 protein exhibits a striking degree of homology with the HSV13 protein which mimics its function. Applications: Suitable for use in ELISA, Immunofluorescence, Flow Cytometry, Neutralization and Western Blot. Other applications not tested. Recommended Dilution: ELISA: ≤2ug/ml Optimal dilutions to be determined by the researcher. Matched Pair: Capture: I8439-04GX Detection: I8439-04A Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.