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I8435-30B

Interleukin 13 Receptor, alpha 2 (FITC)

Size

£698.00

SKU:
I8435-30B
Application:
Flow Cytometry
Purity:
Purified by immunoaffinity chromatography.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Goat
Immunogen:
Recombinant protein corresponding to Cys22-Leu342 from human interleukin 13 receptor alpha 2 expressed in NSO cells.
Format:
Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with Fluorescein isothiocyanate (FITC).
Extra Details:
Two type I membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with high affinity. The lower affinity IL-13 binding protein is now referred to as IL-13 Ra1, is also known as CD213a. IL-13 Ra1 combines with IL-4 Ra to form a high affinity receptor complex capable of transducing an IL-13 dependent proliferative signal. The higher affinity IL-13 binding protein, now referred to as IL-13 Ra2, does not induce a signal and acts as a decoy receptor. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 10ul labels 10e6 cells in A375 human cell line Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice