I8435-05
Interleukin 13 (IL-13)
Size
£314.00
- SKU:
- I8435-05
- Purity:
- Purified by Protein A/G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Purified recombinant human IL-13
- Clone:
- 1.B2.1
- Format:
- Supplied as a liquid in PBS.
- Extra Details:
- IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having structural features and functional characteristics with IL-4. However, it only shares about 30% homology with the IL-4 sequence. IL-13 inhibits IL-1 beta, IL-6, IL-8, and TNF-alpha resulting in anti-inflammatory effects on monocytes and macrophages. It also induces B cells to proliferate and isotype-switch to the production of IgE. In addition, IL-13 modulates TH2 cell development interfering key roles in the ostracizing of gastrointestinal parasites and in the evolvement of asthma and allergy. Applications: Suitable for use in Neutralizing, ELISA, Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 5ug/ml. Detects 100ng of human IL-13 Immunohistochemistry: Frozen sections Note: Further dilutions should be made in in medium or buffered solutions with a carrier protein such as 1% BSA. Optimal dilutions to be determined by researcher. Hybridoma: Rat spleen cells fused with P3X63-AG8.653 myeloma Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice