I8434-29E
IL12A (Interleukin-12 Subunit alpha, IL-12A, Cytotoxic Lymphocyte Maturation Factor 35kD Subunit, CLMF p35, IL-12 Subunit p35, NK Cell Stimulatory Factor Chain 1, NKSF1) (Carboxyfluorescein)
Size
£691.00
- SKU:
- I8434-29E
- Application:
- Flow Cytometry
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Sf 21-derived, recombinant human IL-12 p35 subunit (rhIL-12 p35; Arg23-Ser219; Accession # P29459).
- Clone:
- 11C30
- Format:
- Supplied as a liquid in sodium chloride, 0.5% BSA, 0.09% sodium azide. Labeled with Carboxyfluorescein.
- Extra Details:
- Interleukin 12 (IL-12) and interleukin 35 (IL-35) are heterodimeric cytokines composed of alpha and beta chains. IL-12 is composed of p35 and p40 subunits, while IL-35 is comprised of p35 paired with EBI-3. In mice, IL-35 is produced by FoxP3+ regulatory T cells and may function as an inhibitory cytokine to suppress T cell proliferation. Human FoxP3+ Tregs do not constitutively express IL-35, but expression may be induced by activated dendritic cells. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommened Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: Carboxyfluorescein conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice