Interleukin 12 (IL-12, Cytotoxic Lymphocyte Maturation Factor 1, CTL Maturation Factor, TcMF, CLMF p35, Natural Killer Cell Stimulatory Factor 1, NFSK1, p35, T cell Stimulating Factor, TSF) (FITC)

Size

£838.00

SKU:: I8434-06B-FITC
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Recombinant human IL-12, expresssed in CHO cells.
Format:: Supplied as a liquid in PBS, pH 7.2. Labeled with Fluorescein isothiocyanate (FITC).
Extra Details:: Human IL-12 (Interleukin-12) is a pleiotropic 75kD heterodimeric glycoprotein, consisting of disulfide-linked IL-12A (p35) and IL-12B (p40) subunits, which signals through the high affinity IL-12 receptor. IL-12 is produced primarily by antigen presenting cells and was originally called cytotoxic lymphocyte maturation factor (CLMF), identified by its ability to induce cytotoxic effector cells, in synergy with IL-2. IL-12 is an important factor in the T helper cell (Th1) immune response, promotes the development and activity of activated T cells and natural killer cells (NK), induces IFN-gamma production, and enhances resistance against invading pathogens. Applications: Suitable for use in FLISA, Functional Assays, and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.

Shipping Conditions:: Blue Ice