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I8432-29C

Interleukin 10R, beta (IL-10 R-beta, Interleukin 10 Receptor beta, IL-10R2, CD210b, CRF2-4)

Size

£812.00

SKU:
I8432-29C
Purity:
Purified by Protein G affinity chromatography from hybridoma culture supernatant
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rat
Immunogen:
Recombinant protein corresponding to Ile21-Ser220 from human IL-10R beta, expressed in NS0 cells Species Sequence Homology: rat; 87%, human; 74%
Clone:
10F617
Format:
Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
Extra Details:
IL-10 R-beta (Interleukin 10 receptor beta; also IL-10R2, CD210b and CRF2-4) is an 80-85kD member of the type II cytokine receptor family of proteins. It is very widely expressed and serves as a signal transducing accessory chain when complexed to the ligand-binding chains for IL-10, -22, -28A, -28B, and -29 (plus IL-26 in human). Mature mouse IL-10 R-beta is a type I transmembrane protein with an extracellular domain that possesses two fibronectin type III domains (aa22-107 and 11-208). There is one alternate start site at Met20. Applications: Suitable for use in ELISA and Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 25ug/ml/10e6 cells using EL-4 mouse lymphoblast cell line Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice