I8431
Interleukin 9, Recombinant Human (IL-9)
Size
£332.00
- SKU:
- I8431
- Molecular Weight:
- 14
- Purity:
- ≥98% (SDS-PAGE and HPLC). Endotoxin: ≤0.1ng/ug (1EU/ug).
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Format:
- Supplied as a lyophilized powder with no additives. Reconstituted with sterile ddH2O to a concentration of 0.1-1.0mg/ml. Do not vortex.
- Extra Details:
- IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin's disease. Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells. Recombinant human IL-9 is a 14.kD protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins. Recombinant protein corresponding to human IL-9, expressed in E. coli. Amino Acid Sequence: MQGCPTLAGI LDINFLINKM QEDPASKCHC SANVTSCLCL GIPSDNCTRP CFSERLSQMT NTTMQTRYPL IFSRVKKSVE VLKNNKCPYF SCEQPCNQTT AGNALTFLKS LLEIFQKEKM RGMRGKI Biological Activity: Determined by its ability to stimulate the proliferation of human MO7e cells. The expected ED50 is <0.2ng/ml, corresponding to a specific activity of >5x10e6units/mg. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Ambient