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I8431-75DX

CD129 (Interleukin-9 Receptor, IL-9 Receptor, IL-9R, IL9R) (Low Endotoxin, Azide Free)

Size

£512.00

SKU:
I8431-75DX
Purity:
Purified by Protein A affinity chromatography.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Mouse
Immunogen:
Human CD129-transfected cell line
Clone:
AH9R7
Format:
Supplied as a liquid in PBS, pH 7.4. No preservative added.
Extra Details:
CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma. Applications: Suitable for use in Functional Assays, ELISA and Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: it is recommended to use bright fluorochromes or signal multiplying detection. Functional Assays: Blocking Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice