I8429-27M3

Interleukin 7 Receptor alpha (Interleukin-7 Receptor Subunit alpha, IL-7 Receptor Subunit alpha, IL-7R Subunit alpha, IL-7R-alpha, IL7RA, IL-7RA, IL7R, CD127, CDw127, ILRA) (FITC)

Size

£639.00

SKU:: I8429-27M3
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant correspponding to human CD127.
Clone:: 11K10
Format:: Supplied as liquid in 50mM sodium phosphate pH 7.5, 100mM potassium chloride, 150mM sodium chloride, 0.2% BSA, 0.04% sodium azide, 5% glycerol. Labeled with fluorescein isothiocyanate (FITC).
Extra Details:: CD127 (IL-7R alpha) is the specific receptor component for the cytokine Interleukin -7 (IL-7). It is found on a wide variety of hematopoietic cell types including B cell precursors, and the majority of T cells. Its expression levels are decreased on T cells following activation. CD127 can dimerize with CD132 (IL-2R gamma) to form a high affinity IL-7 receptor (1). CD127 engagement is necessary for T cell development in humans (2). Applications: Suitable for use in FLISA and Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.