I8428-16E

Interleukin 6 (IL-6)

Size

£1,068.00

SKU:: I8428-16E
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Format:: Supplied as a liquid in PBS, 0.1% BSA.
Extra Details:: IL-6 is a pluripotent 20-22kD cytokine which plays a role in the pathophysiology of severe infection and regulates the immune response, acute phase reaction and hematopoiesis. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. Continuous IL-6 gene expression makes an essential contribution to a multistep oncogenesis of plasma cell neoplasia. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas. Applications: Suitable for use in Functional Studies, Western Blot and ELISA. Other applications not tested. Recommended Dilution: Western Blot: 1:10 ELISA: 1:10 Functional Studies: can be used for neutralization of mouse and rat IL-6 in bio-assays. For neutralization of biological activity dilutions have to be made according to the amounts IL-6 to be inactivated. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.