I8426-70D
Interleukin 4 Receptor (IL-4R)
Size
£594.00
- SKU:
- I8426-70D
- Purity:
- Purified by Protein A affinity chromatography from ascites
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant human interleukin 4 receptor, extracellular domain, expressed in Sf21 cell line
- Clone:
- 10B2405 (25463 (49/20))
- Format:
- Supplied as a liquid in PBS, 0.5% trehalose
- Extra Details:
- CD124 is a 825 amino acid ~90kDa type I single pass transmembrane glycoprotein bearing a single fibronectin type III domain. Interleukin-4 Receptor form a heterodimeric complex with the cytokine receptor common subunit gamma, referred to as the IL-4 type-1 complex. The alpha subunit can also form the type-II complex through association with the IL-13 receptor alpha 1 subunit. The IL-4R complex acts as a receptor for both interleukin-4 and interleukin-13. IL-4 R is expressed by B cells, T cells, monocytes and macrophages. Applications: Suitable for use in ELISA, Flow Cytometry, Western Blot, Immunohistochemistry and Fuctional Assays. Other applications not tested. Recommended Dilutions: ELISA: 1:250-1:1000 Flow Cytometry: 1:10-1:40 Immunohistochemistry (Paraffin): 1:20-1:60 Western Blot: 1:125-1:500 detects human IL-4R under non-reducing conditions Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice